Article

Genetic deletion of β-arrestin 2 modulates LSD-stimulated behaviors in mice

2021-05-26

Abstract excerpt

Recent evidence suggests that psychedelic drugs can exert beneficial effects on anxiety, depression, and ethanol and nicotine abuse in humans. However, their hallucinogenic side-effects often preclude their clinical use. Lysergic acid diethylamide (LSD) is a prototypical hallucinogen and its psychedelic actions are exerted through the 5-HT2A serotonin receptor (5-HT2AR). 5-HT2AR activation stimulates Gq- and β-arr...

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Literature Corpus work: c3bf2441-ba7d-561a-8089-174652f5d4df
DOI: 10.21203/rs.3.rs-544199/v1

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