Article

A suite of engineered mice for interrogating psychedelic drug actions

2023-09-26

Abstract excerpt

<h4>ABSTRACT</h4> Psychedelic drugs like lysergic acid diethylamide (LSD) and psilocybin have emerged as potentially transformative therapeutics for many neuropsychiatric diseases, including depression, anxiety, post-traumatic stress disorder, migraine, and cluster headaches. LSD and psilocybin exert their psychedelic effects via activation of the 5-hydroxytryptamine 2A receptor (HTR2A). Here we provide a suite o...

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Literature Corpus work: 4ded7473-3436-579f-b8c1-f687abd18a2b
DOI: 10.1101/2023.09.25.559347

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