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Article

Phenotypic analysis of GalR2 knockout mice in anxiety- and depression-related behavioral tests.

Neuropeptides - 1 Aug 2008

Lu Xiaoying, Ross Brendon, Sanchez-Alavez Manuel, Zorrilla Eric P, Bartfai Tamas

Abstract excerpt

Neuropeptide galanin modulates a variety of central nervous system functions by signaling through three G-protein-coupled receptor subtypes, GalR1 through GalR3. Galanin and its receptors are expressed at high levels in the limbic structures of the rodent brain. Intracerebroventricular injection of galanin has been shown to modulate depression and anxiety-like behaviors in the rat. We have previously shown that...

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Identifiers

PMID: 18554714
DOI: 10.1016/j.npep.2008.04.009
PMCID: PMC3399724

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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