Article

The serotonin 1B receptor is required for some of the behavioral effects of psilocybin in mice

2024-10-21

Abstract excerpt

Recent studies highlight the promising use of psychedelic therapies for psychiatric disorders, including depression. The persisting clinical effects of psychedelics such as psilocybin are commonly attributed to activation of the serotonin 2A receptor (5-HT2AR) based on its role in the acute hallucinatory effects. However, the active metabolite of psilocybin binds to many serotonin receptor subtypes, including the...

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Literature Corpus work: 5aee15c8-1df4-552a-ad7d-b52ec799816b
DOI: 10.1101/2024.10.18.618582

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