Article

Cell type specific genetic regulation of gene expression across human tissues

2019-10-16

Abstract excerpt

The Genotype-Tissue Expression (GTEx) project has identified expression and splicing quantitative trait loci ( cis -QTLs) for the majority of genes across a wide range of human tissues. However, the interpretation of these QTLs has been limited by the heterogeneous cellular composition of GTEx tissue samples. Here, we map interactions between computational estimates of cell type abundance and genotype to identify...

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Literature Corpus work: c31a8299-afdd-5132-b15e-b9e34d4cea46
DOI: 10.1101/806117

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