Article
Genetic effects on gene expression across human tissues.
Nature - 11 Oct 2017
Battle Alexis, Brown Christopher D, Engelhardt Barbara E, Montgomery Stephen B
Abstract excerpt
Characterization of the molecular function of the human genome and its variation across individuals is essential for identifying the cellular mechanisms that underlie human genetic traits and diseases. The Genotype-Tissue Expression (GTEx) project aims to characterize variation in gene expression levels across individuals and diverse tissues of the human body, many of which are not easily accessible. Here we...
Topics
- Alleles
- Chromosomes, Human
- Disease
- Female
- Gene Expression Profiling
- Gene Expression Regulation
- Genetic Variation
- Genome, Human
- Genotype
- Humans
- Male
- Organ Specificity