Article
A compendium of uniformly processed human gene expression and splicing quantitative trait loci.
Nature genetics - 1 Sept 2021
Kerimov Nurlan, Hayhurst James D, Peikova Kateryna, Manning Jonathan R, Walter Peter, Kolberg Liis, Samoviča Marija, Sakthivel Manoj Pandian, Kuzmin Ivan, Trevanion Stephen J, Burdett Tony, Jupp Simon, Parkinson Helen, Papatheodorou Irene, Yates Andrew D, Zerbino Daniel R, Alasoo Kaur
Abstract excerpt
Many gene expression quantitative trait locus (eQTL) studies have published their summary statistics, which can be used to gain insight into complex human traits by downstream analyses, such as fine mapping and co-localization. However, technical differences between these datasets are a barrier to their widespread use. Consequently, target genes for most genome-wide association study (GWAS) signals have still not...
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