Article

Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

2021-12-23

Abstract excerpt

The SARS-CoV-2 B.1.1.529 (Omicron) variant contains 15 mutations of the receptor-binding domain (RBD). How Omicron evades RBD-targeted neutralizing antibodies requires immediate investigation. Here we use high-throughput yeast display screening1,2 to determine the profiles of RBD escaping mutations for 247 human anti-RBD neutralizing antibodies and show that the neutralizing antibodies can be classified by unsuper...

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Literature Corpus work: c2f30f6d-ab91-59a6-8ec4-549ee32270de
DOI: 10.1038/d41586-021-03796-6

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