Article

B.1.1.529 escapes the majority of SARS-CoV-2 neutralizing antibodies of diverse epitopes

2021-12-08

Abstract excerpt

<title>Abstract</title> <p>The SARS-CoV-2 B.1.1.529 variant (Omicron) contains 15 mutations on the receptor-binding domain (RBD). How Omicron would evade RBD neutralizing antibodies (NAbs) and humoral immunity requires immediate investigation. Here, we used high-throughput yeast display screening1,2 to determine the RBD escaping mutation profiles for 247 human anti-RBD NAbs identified from SARS-CoV/SARS-CoV-2 con...

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Literature Corpus work: 9493d935-4225-571c-8643-3097d9250ee9
DOI: 10.21203/rs.3.rs-1148985/v1

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