Article

An eQTL-based Approach Reveals Candidate Regulators of LINE-1 RNA Levels in Lymphoblastoid Cells

2023-08-17

Abstract excerpt

Long interspersed element 1 (L1) are a family of autonomous, actively mobile transposons that occupy ∼17% of the human genome. A number of pleiotropic effects induced by L1 (promoting genome instability, inflammation, or cellular senescence) have been observed, and L1’s contributions to aging and aging diseases is an area of active research. However, because of the cell type-specific nature of transposon control,...

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Literature Corpus work: c2d5cc3f-3b11-5d67-b840-34fe19992349
DOI: 10.1101/2023.08.15.553416

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