Article

Evolutionary arms race between transposable elements and human genes: telomere-to-telomere genome comprehensive analysis identifies young L1 clusters in the interferon-alpha domain

2026-04-17

Abstract excerpt

Transposable elements (TEs) have played a central role in major evolutionary transitions across the human lineage, from eukaryogenesis to the emergence of the eutherian placenta, and are currently reactivated in cancer and autoimmune diseases. The availability of the complete telomere-to-telomere (T2T) human genome assembly enables comprehensive investigation of TE contributions to gene regulation. Using a 10 kb w...

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Literature Corpus work: 897afc03-f4bb-5f3c-9ddc-1ae856dd331d
DOI: 10.32942/x2fm2m

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