Article

Hereditary haemochromatosis beyond liver cancer: increased risk of prostate cancer during an 11-year follow-up

2022-02-28

Abstract excerpt

In European ancestry populations, the iron overload disorder Hereditary Haemochromatosis (HH) is predominantly caused by the HFE p.C282Y mutation. Male p.C282Y homozygotes have markedly increased hepatic malignancy risks but risks for other cancers in both male and female homozygotes are unclear. We studied data from 451,143 UK Biobank European ancestry community participants (aged 40-70 years; 54.3% female) follo...

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Literature Corpus work: c1e9f04f-e0d8-5b54-98fa-9ac59007e7c8
DOI: 10.1101/2022.02.28.22271621

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