Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Common conditions associated with hereditary haemochromatosis genetic variants: cohort study in UK Biobank

16 Jan 2019

Abstract excerpt

Abstract Objective To compare prevalent and incident morbidity and mortality between those with the HFE p.C282Y genetic variant (responsible for most hereditary haemochromatosis type 1) and those with no p.C282Y mutations, in a large UK community sample of European descent. Design Cohort study. Setting 22 centres across England, Scotland, and Wales in UK Biobank (2006-10). Participants 451 243 volunteers of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hemoglobinopathies and Related Disorders
Share to Iron Metabolism and Disorders
Share to Trace Elements in Health

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30651232
DOI: 10.1136/bmj.k5222

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 19 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Common conditions associated with hereditary haemochromatosis genetic variants: cohort study in UK BiobankPMID 30651232Read ↗

<i>HFE</i>genotypes, haemochromatosis diagnosis and clinical outcomes to age 80: a prospective cohort study in UK BiobankSemantic proximity Read ↗

HFE genotypes, haemochromatosis diagnosis and clinical outcomes at age 80 years: a prospective cohort study in the UK Biobank.Semantic proximity Read ↗

Genetic and lifestyle modifiers of haemochromatosis-related clinical outcomes in HFE C282Y homozygotes: prospective cohort study in UK BiobankSemantic proximity Read ↗

Haemochromatosis genetic variants and musculoskeletal outcomes: 11.5 year follow-up in the UK Biobank cohort studySemantic proximity Read ↗

Penetrance of <i>HFE</i> haemochromatosis variants to clinical disease: polygenic risk score associations in UK BiobankSemantic proximity Read ↗

The landscape of hereditary haemochromatosis risk and diagnosis across the British Isles and Ireland.Semantic proximity Read ↗

Hereditary Hemochromatosis Variant Associations with Incident Nonliver Malignancies: 11-Year Follow-up in UK Biobank.Semantic proximity Read ↗

Association of Hemochromatosis HFE p.C282Y Homozygosity With Hepatic Malignancy.Semantic proximity Read ↗

HFE-associated hereditary hemochromatosis: overview of genetics and clinical implications for nurse practitioners in primary care settings.Semantic proximity Read ↗

Clinical manifestations of hemochromatosis in HFE C282Y homozygotes identified by screening.Semantic proximity Read ↗

Unraveling genotype-phenotype relationships in hereditary hemochromatosis through integrated biobank data analysis.Semantic proximity Read ↗

Hereditary haemochromatosis beyond liver cancer: increased risk of prostate cancer during an 11-year follow-upSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.