Article

<i>HFE</i>genotypes, haemochromatosis diagnosis and clinical outcomes to age 80: a prospective cohort study in UK Biobank

2023-11-17

Abstract excerpt

<h4>Objectives</h4> HFE haemochromatosis genetic variants have an uncertain clinical penetrance, especially to older ages and in undiagnosed groups. We estimated p.C282Y and p.H63D variant cumulative incidence of multiple clinical outcomes in a large community cohort. <h4>Design</h4> Prospective cohort study. <h4>Setting</h4> 22 assessment centres across England, Scotland, and Wales in the UK Biobank (2006-2010)....

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Literature Corpus work: ed7837a8-e295-5dcb-9a16-5ee975f165c8
DOI: 10.1101/2023.11.17.23298637

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