Article

Evolutionary Advantage of the Diversity-Generating Retroelement Hypermutating System

2026-02-18

Abstract excerpt

Diversity-Generating Retroelements (DGRs) create rapid, targeted variation within specific genomic regions in phages and bacteria. They operate through stochastic retro-transcription of a template region (TR) into a variable region (VR), which typically encodes ligand-binding proteins. Despite their prevalence, the conditions under which maintaining such hypermutating system is favorable remain unclear. Here we in...

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Literature Corpus work: c18f70a6-e7db-5f9f-8b21-628858abe30c
DOI: 10.64898/2026.02.18.706561

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