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Article

Selective ligand recognition by a diversity-generating retroelement variable protein.

PLoS biology - 3 Jun 2008

Miller Jason L, Le Coq Johanne, Hodes Asher, Barbalat Roman, Miller Jeff F, Ghosh Partho

Abstract excerpt

Diversity-generating retroelements (DGRs) recognize novel ligands through massive protein sequence variation, a property shared uniquely with the adaptive immune response. Little is known about how recognition is achieved by DGR variable proteins. Here, we present the structure of the Bordetella bacteriophage DGR variable protein major tropism determinant (Mtd) bound to the receptor pertactin, revealing...

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Share to Bacterial Outer Membrane Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18532877
DOI: 10.1371/journal.pbio.0060131
PMCID: PMC2408619

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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