Article
Mutational heterogeneity: a key ingredient of bet-hedging and evolutionary divergence?: The broad spectrum of mutations and their flexible frequency in populations provides a source of risk avoidance and alternative evolutionary strategies.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Feb 2015
Ferenci Thomas, Maharjan Ram
Abstract excerpt
Here, we propose that the heterogeneity of mutational types in populations underpins alternative pathways of evolutionary adaptation. Point mutations, deletions, insertions, transpositions and duplications cause different biological effects and provide distinct adaptive possibilities. Experimental evidence for this notion comes from the mutational origins of adaptive radiations in large, clonal bacterial...
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