Article

Coordinated poleward flux of sister kinetochore fibers drives chromosome alignment

2021-01-01

Abstract excerpt

<h4>ABSTRACT</h4> Chromosome alignment at the spindle equator promotes proper chromosome segregation and depends on pulling forces exerted at kinetochore fiber tips together with polar ejection forces. However, kinetochore fibers are also subjected to forces driving their poleward flux. Here we introduce a flux-driven centering model that relies on flux generated by forces within the overlaps of bridging and kine...

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Literature Corpus work: c14ac715-0453-5423-a431-0788cca7fca8
DOI: 10.1101/2020.12.30.424837

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