Article

Augmin prevents merotelic attachments by promoting proper arrangement of bridging and kinetochore fibers

2020-09-10

Abstract excerpt

<h4>ABSTRACT</h4> The human mitotic spindle is made of microtubules nucleated at centrosomes, at kinetochores, and from pre-existing microtubules by the augmin complex. However, it is unknown how the augmin-mediated nucleation affects distinct microtubule classes and thereby mitotic fidelity. Here we use superresolution microscopy to analyze the previously indistinguishable microtubule arrangements within the cro...

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Literature Corpus work: b8647f1b-cded-5fa9-8e3e-156232237c88
DOI: 10.1101/2020.09.10.291740

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