Article

Survivin Regulates Intracellular Stiffness and Extracellular Matrix Production in Vascular Smooth Muscle Cells

2022-10-24

Abstract excerpt

<h4>ABSTRACT</h4> Vascular dysfunction is a common cause of cardiovascular diseases characterized by the narrowing and stiffening of arteries, such as atherosclerosis, restenosis, and hypertension. Arterial narrowing results from the aberrant proliferation of vascular smooth muscle cells (VSMCs) and their increased synthesis and deposition of extracellular matrix (ECM) proteins. These, in turn, are modulated by a...

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Literature Corpus work: 8d4cdd8f-4437-5b8c-924e-ea82588bf309
DOI: 10.1101/2022.10.24.513582

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