Article

Matrix stiffness-induced transcriptome alterations and regulatory mechanisms revealed by RNA-seq in Endothelial cells

2022-09-20

Abstract excerpt

<title>Abstract</title> <p>Background Changes in vascular stiffness are associated with the development and progression of many diseases, especially in cardiovascular disease. However, the effect of vascular stiffness on the endothelial cells (ECs) is not fully understood. This study focused on the transcriptional profiles of ECs cultured on the matrices with different stiffness (1kPa and 40kPa, respectively) to...

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Literature Corpus work: 529c09ae-bec6-5695-9d56-240c8dd9e647
DOI: 10.21203/rs.3.rs-2016915/v1

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