Article
Tuning of collagen scaffold properties modulates embedded endothelial cell regulatory phenotype in repair of vascular injuries in vivo.
Advanced healthcare materials - 28 Oct 2015
Unterman Shimon, Freiman Alina, Beckerman Margarita, Abraham Eytan, Stanley James R L, Levy Ela, Artzi Natalie, Edelman Elazer
Abstract excerpt
Perivascularly implanted matrix embedded endothelial cells (MEECs) are potent regulators of inflammation and intimal hyperplasia following vascular injuries. Endothelial cells (ECs) in collagen scaffolds adopt a reparative phenotype with significant therapeutic potential. Although the biology of MEECs is increasingly understood, tuning of scaffold properties to control cell-substrate interactions is less...
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