Article

Identifying Genetic Regulatory Variants that Affect Transcription Factor Activity

2022-10-21

Abstract excerpt

<h4>SUMMARY</h4> Assessing the functional impact of genetic variants across the human genome is essential for understanding the molecular mechanisms underlying complex traits and disease risk. Genetic variation that causes changes in gene expression can analyzed through parallel genotyping and functional genomics assays across sets of individuals. Trans-acting variants are of particular interest, but more challen...

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Literature Corpus work: 7731e68d-5298-5e39-a7d6-3e68d0836236
DOI: 10.1101/2022.10.21.513166

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