Article

Alternative promoters used during myeloid differentiation and upon activation change the gene products available for innate immune programs

2026-02-03

Abstract excerpt

Macrophages are innate immune cells present in most tissues of the body, whose molecular programs are determined by their ontogeny and environment. From the earliest stages of embryonic development, macrophages are recruited into developing tissues where they support organogenesis with trophic factors such as WNT, VEGF and PDGF. While macrophage subsets have been described in different tissues at single cell resol...

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Literature Corpus work: c08caba7-6980-508c-bd60-a6c4328fb47c
DOI: 10.64898/2026.02.01.703142

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