Article
Differential gene expression in human, murine, and cell line-derived macrophages upon polarization.
Experimental cell research - 10 Sept 2016
Spiller Kara L, Wrona Emily A, Romero-Torres Saly, Pallotta Isabella, Graney Pamela L, Witherel Claire E, Panicker Leelamma M, Feldman Ricardo A, Urbanska Aleksandra M, Santambrogio Laura, Vunjak-Novakovic Gordana, Freytes Donald O
Abstract excerpt
The mechanisms by which macrophages control the inflammatory response, wound healing, biomaterial-interactions, and tissue regeneration appear to be related to their activation/differentiation states. Studies of macrophage behavior in vitro can be useful for elucidating their mechanisms of action, but it is not clear to what extent the source of macrophages affects their apparent behavior, potentially affecting...
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