Article

Isoform-level transcriptome Atlas of Macrophage Activation

2020-12-21

Abstract excerpt

RNA-seq is routinely used to measure gene expression changes in response to cell perturbation. Genes that are up or down-regulated following perturbation in RNA-seq studies are designated as target genes for follow-up. However, RNA-seq is limited in its ability to capture the complexity of gene isoforms, defined by the exact composition of exons and transcription start sites (TSS) and poly(A) sites they contain, a...

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Literature Corpus work: 333f3e81-212e-5a0f-b908-7a810f7d7f75
DOI: 10.1101/2020.12.20.423532

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