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Article

Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation

1 Feb 2014

Abstract excerpt

Macrophage activation is associated with profound transcriptional reprogramming. Although much progress has been made in the understanding of macrophage activation, polarization, and function, the transcriptional programs regulating these processes remain poorly characterized. We stimulated human macrophages with diverse activation signals, acquiring a data set of 299 macrophage transcriptomes. Analysis of this...

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PMID: 24530056
DOI: 10.1016/j.immuni.2014.01.006

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