Article
Tissue-specific and ubiquitous expression patterns from alternative promoters of human genes.
PloS one - 18 Aug 2010
Jacox Edwin, Gotea Valer, Ovcharenko Ivan, Elnitski Laura
Abstract excerpt
BACKGROUND: Transcriptome diversity provides the key to cellular identity. One important contribution to expression diversity is the use of alternative promoters, which creates mRNA isoforms by expanding the choice of transcription initiation sites of a gene. The proximity of the basal promoter to the transcription initiation site enables prediction of a promoter's location based on the gene annotations. We show...
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