Article

Chromatin remodeling (SWI/SNF) complexes, cancer, and response to immunotherapy

2022-09-01

Abstract excerpt

Chromatin regulation involves four subfamilies composed of ATP-dependent multifunctional protein complexes that remodel the way DNA is packaged. The SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin remodeling complex subfamily mediates nucleosome reorganization and hence activation/repression of critical genes. The SWI/SNF complex is composed of the BRG-/BRM-associated factor and Polybromo-associated BAF complex...

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Literature Corpus work: bf649ce9-082e-5d75-bb9b-d63822edf7ee
DOI: 10.1136/jitc-2022-004669

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