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Article

SWI/SNF Complexes in Ovarian Cancer: Mechanistic Insights and Therapeutic Implications.

Molecular cancer research : MCR - 1 Dec 2018

Fukumoto Takeshi, Magno Elizabeth, Zhang Rugang

Abstract excerpt

Ovarian cancer remains the most lethal gynecologic malignancy in the developed world. Despite the unprecedented progress in understanding the genetics of ovarian cancer, cures remain elusive due to a lack of insight into the mechanisms that can be targeted to develop new therapies. SWI/SNF chromatin remodeling complexes are genetically altered in approximately 20% of all human cancers. SWI/SNF alterations vary in...

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Identifiers

PMID: 30037854
DOI: 10.1158/1541-7786.MCR-18-0368
PMCID: PMC6279546

Genes

CARM1
SMARCA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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