Article
Impact of Mutations in Subunit Genes of the Mammalian SWI/SNF Complex on Immunological Tumor Microenvironment.
Cancer genomics & proteomics - 1 Jan 2000
Hozumi Chikako, Iizuka Akira, Ikeya Tomoatsu, Miyata Haruo, Maeda Chie, Ashizawa Tadashi, Nagashima Takeshi, Urakami Kenichi, Shimoda Yuji, Ohshima Keiichi, Muramatsu Koji, Sugino Takashi, Shiomi Akio, Ohde Yasuhisa, Bando Etsuro, Furukawa Kenichiro, Sugiura Teiichi, Mukaigawa Takashi, Nishimura Seiichiro, Hirashima Yasuyuki, Mitsuya Koichi, Yoshikawa Shusuke, Tsubosa Yasuhiro, Katagiri Hirohisa, Niwakawa Masashi, Yamaguchi Ken, Kenmotsu Hirotsugu, Akiyama Yasuto
Abstract excerpt
BACKGROUND/AIM: Recently, inactivating somatic mutations of SWI/SNF chromatin-remodeling genes in cancers have been reported. However, few studies have been performed regarding the immunological analysis of the tumor microenvironment (TME) in chromatin remodeling complex gene-mutated tumors. In the present study, we identified cancer patients harboring various mammalian SWI/SNF complex mutations and investigated...
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