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Inflammatory Signature in Acute-on-Chronic Liver Failure Includes Increased Expression of Neutrophil Specific Genes ELANE, MPO and CD177 Running Title: Neutrophil Transcriptomics in ACLF

2021-05-18

Abstract excerpt

<h4>Background and Aims: </h4> Acute-on-Chronic Liver Failure (ACLF) is associated with innate immune dysfunction and high short-term mortality. Neutrophils have been identified to influence prognosis in ACLF. Neutrophil biology is under-evaluated in ACLF. Therefore, we investigated neutrophil-specific genes and their association with ACLF outcomes. <h4>Methods: </h4>: This is an observational study. Enriched poly...

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Literature Corpus work: bf5f3e0c-a04b-5276-bbc7-17fae75ee987
DOI: 10.21203/rs.3.rs-537123/v1

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