Article

Characterizing a Low-Density Neutrophil gene signature in acute and chronic infections and its impact on disease severity

2024-11-04

Abstract excerpt

Low-density neutrophils (LDNs) or polymorphonuclear myeloid-derived suppressor cells (PMN-MDSC) are involved in the pathogenesis of cancer, autoimmune and infectious diseases. They are crucial in the host-response to invading pathogens, especially during acute illness, and are associated with poor prognosis in many infectious diseases. However, their gene expression profile and contribution to disease outcomes are...

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Literature Corpus work: c4351d76-128b-5b6b-b4e6-a1549fa31491
DOI: 10.1101/2024.11.01.621545

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