Article
Circulating Neutrophil Dysfunction in HBV-Related Acute-on-Chronic Liver Failure.
Frontiers in immunology - 1 Jan 2021
Wu Wei, Sun Shanshan, Wang Yijie, Zhao Ruihong, Ren Haotang, Li Zhiwei, Zhao Hong, Zhang Yi, Sheng Jifang, Chen Zhi, Shi Yu
Abstract excerpt
Background and Aims: Acute-on-chronic liver failure (ACLF) is characterized by systemic inflammation accompanied by defective anti-bacterial immunity. The role of neutrophils in immune derangement of ACLF has not been fully elucidated. This study is aimed to characterize the role of circulating neutrophils in HBV-related ACLF patients. Methods: Quantitative, phenotypic, transcriptomic, and functional alterations...
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