Article

Acute-on-Chronic Liver Failure: An Eroded Cliff Hit by a Storm – A Narrative Review

2026-06-22

Abstract excerpt

Acute-on-chronic liver failure (ACLF) is a rapidly progressing and highly lethal clinical syndrome characterized by multiorgan failure, driven primarily by a severe systemic inflammatory response. The pathophysiological cascade, triggered by an initial “cytokine storm,” subsequently evolves into profound immune paralysis. This phenomenon is driven by the dysfunction of monocytes, neutrophils, and other immune cell...

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Literature Corpus work: d5784f3c-5bc6-5fec-8cb7-b2b8628b328f
DOI: 10.20944/preprints202606.1550.v1

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