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Article

Integrated transcriptomic and phenotypic analyses reveal spatiotemporal variation in neutrophil Cd14 expression after hepatectomy.

PloS one - 1 Jan 2026

Adawy Ahmad, Honda Masaki, Yoshii Daiki, Hirao Hiroki, Tomita Masahiro, Shimata Keita, Komohara Yoshihiro, Hibi Taizo

Abstract excerpt

Neutrophils are key mediators of both hepatic injury and repair. This study aimed to characterize the spatiotemporal dynamics of Cd14 expression in neutrophils following hepatectomy and to explore its potential role in liver regeneration. We performed an integrated transcriptomic and phenotypic analysis of neutrophil Cd14 expression using bioinformatics and flow cytometry in immune cells isolated from murine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42611863
DOI: 10.1371/journal.pone.0356246
PMCID: PMC13484978

Genes

CD14
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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