Article

Cholesterol sensing by CD81 is important for hepatitis C virus entry

2019-02-06

Abstract excerpt

CD81 plays a central role in a variety of physiological and pathological processes. Recent structural analysis of CD81 indicates that it contains an intramembrane cholesterol-binding pocket and that interaction with cholesterol may regulate a conformational opening of the large extracellular domain of CD81. Therefore, CD81 possesses a potential cholesterol sensing mechanism; however, the relevance of this for prot...

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Literature Corpus work: bf33d801-d5d1-5664-9d7f-09cda5d9ae0b
DOI: 10.1101/542837

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