Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Building a mechanistic mathematical model of hepatitis C virus entry

18 Mar 2019

Abstract excerpt

The mechanism by which hepatitis C virus (HCV) gains entry into cells is a complex one, involving a broad range of host proteins.Entry is a critical phase of the viral lifecycle, and a potential target for therapeutic or vaccine-mediated intervention.However, the mechanics of HCV entry remain poorly understood.Here we describe a novel computational model of viral entry, encompassing the relationship between HCV...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis B Virus Studies
Share to Hepatitis C virus research
Share to Liver Disease Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30883541
DOI: 10.1371/journal.pcbi.1006905

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Building a mechanistic mathematical model of hepatitis C virus entryPMID 30883541Read ↗

Mathematical Model of Viral Kinetics In Vitro Estimates the Number of E2-CD81 Complexes Necessary for Hepatitis C Virus EntrySemantic proximity Read ↗

Hepatitis C virus entry: beyond receptorsSemantic proximity Read ↗

Modeling Suggests a Mechanism of Synergy Between Hepatitis C Virus Entry Inhibitors and Drugs of Other ClassesSemantic proximity Read ↗

How hepatitis E virus invades hepatocytes: the mystery of viral entrySemantic proximity Read ↗

Scavenger receptor class B type I is more conducive for genotype 1b hepatitis C virus internalization than low-density lipoprotein receptor.Semantic proximity Read ↗

Mutations that alter use of hepatitis C virus cell entry factors mediate escape from neutralizing antibodies.Semantic proximity Read ↗

Quantitative Proteomics Identifies Serum Response Factor Binding Protein 1 as a Host Factor for Hepatitis C Virus EntrySemantic proximity Read ↗

Hepatitis C Virus Envelope Glycoproteins: A Balancing Act of Order and DisorderSemantic proximity Read ↗

Intracellular Hepatitis C Virus Modeling Predicts Infection Dynamics and Viral Protein MechanismsSemantic proximity Read ↗

Dynamics of Virus-Receptor Interactions in Virus Binding, Signaling, and EndocytosisSemantic proximity Read ↗

Cholesterol sensing by CD81 is important for hepatitis C virus entrySemantic proximity Read ↗

Characterization of host-range and cell entry properties of the major genotypes and subtypes of hepatitis C virus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.