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Article

An intramolecular bond at cluster of differentiation 81 ectodomain is important for hepatitis C virus entry.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Oct 2015

Yang Wei, Zhang Meng, Chi Xiaojing, Liu Xiuying, Qin Bo, Cui Sheng

Abstract excerpt

Hepatitis C virus (HCV) infection is one of the leading causes of chronic liver diseases; however, HCV vaccine remains unavailable to date. One main obstacle is the lack of an efficient small animal model. Cluster of differentiation 81 (CD81) is an essential entry coreceptor for HCV species specificity to humans, though the underlying mechanisms are yet to be fully elucidated. We performed structural,...

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Identifiers

PMID: 26116703
DOI: 10.1096/fj.15-272880

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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