Article

Mutation-specific reporter for optimization and enrichment of prime editing

2021-09-09

Abstract excerpt

<title>Abstract</title> <p>Prime editing is a versatile genome-editing technique. However, some genomic sites remain difficult to edit and optimal design of prime-editing tools is elusive. We present a fluorescent prime editing and enrichment reporter (fluoPEER), which can be tailored to any genomic target site. This system rapidly and faithfully ranked the efficiency of prime edit guide RNAs (pegRNAs) and any pr...

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Literature Corpus work: bf2b13fa-01a0-5ab4-8d56-9b2c7788cf0e
DOI: 10.21203/rs.3.rs-563512/v1

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