Article
Development of Plant Prime-Editing Systems for Precise Genome Editing.
Plant communications - 11 May 2020
Xu Rongfang, Li Juan, Liu Xiaoshuang, Shan Tiaofeng, Qin Ruiying, Wei Pengcheng
Abstract excerpt
Prime-editing systems have the capability to perform efficient and precise genome editing in human cells. In this study, we first developed a plant prime editor 2 (pPE2) system and test its activity by generating a targeted mutation on an HPT-ATG reporter in rice. Our results showed that the pPE2 system could induce programmable editing at different genome sites. In transgenic T0 plants, pPE2-generated mutants...
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