Article
Comparative analysis of syngeneic mouse models of high-grade serous ovarian cancer
2023-03-10
Abstract excerpt
Ovarian cancers often exhibit high rates of recurrence and poor treatment response. Preclinical models that recapitulate the heterogeneity of human disease are critical to develop new therapeutic approaches. While patient-derived models are a powerful tool for testing various therapeutics, their dependence on immune-compromised mice is severely limiting. Syngeneic mouse models, however, allow for the generation of...
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Identifiers and source
- Literature Corpus work
- bf09bfdb-cc02-57dd-a51c-bf0439b3b637
- DOI
- 10.1101/2023.03.09.531888