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Comparative analysis of syngeneic mouse models of high-grade serous ovarian cancer

13 Nov 2023

Abstract excerpt

Ovarian cancers exhibit high rates of recurrence and poor treatment response. Preclinical models that recapitulate human disease are critical to develop new therapeutic approaches. Syngeneic mouse models allow for the generation of tumours comprising the full repertoire of non-malignant cell types but have expanded in number, varying in the cell type of origin, method for transformation, and ultimately, the...

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PMID: 37957414
DOI: 10.1038/s42003-023-05529-z

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