Article
Genetically engineered mouse models for epithelial ovarian cancer: are we there yet?
Seminars in cell & developmental biology - 1 Mar 2014
Howell Viive M
Abstract excerpt
The development of preclinical spontaneous genetically engineered mouse models (GEMMs) requires an understanding of the genetic basis of the human disease. Such robust models have proven invaluable for increasing understanding of human malignancies as well as identifying new biomarkers and testing new therapies for these diseases. While GEMMs have been reported for ovarian cancer, the majority have proven...
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