Article

Investigating guanylate binding protein-mediated restriction of Toxoplasma gondii in murine and human cells

2021-01-01

Abstract excerpt

The guanylate binding proteins (GBPs) are a family of 65-73kDa IFN-inducible GTPases, conserved among vertebrates, with several reported functions in intrinsic immunity to intracellular pathogens. Murine GBPs (mGBP) and human GBPs (hGBP) have been shown to contribute to IFNg-mediated immunity against the apicomplexan parasite Toxoplasma gondii. In this thesis, I seek to expand our knowledge of mGBP- and hGBP-media...

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Literature Corpus work: beee728d-ccf0-51f0-a10b-9c3474307370
DOI: 10.25560/89327

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