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Novel tumor suppressor roles for <i>GZMA</i> and <i>RASGRP1</i> in dissemination of both <i>Theileria annulata</i> -transformed macrophages and human B-lymphoma cells

2018-06-04

Abstract excerpt

Theileria annulata is a tick-transmitted apicomplexan parasite that infects and transforms bovine leukocytes into disseminating tumors that cause a disease called tropical theileriosis. Using comparative transcriptomics we identified genes transcriptionally perturbed during Theileria -induced transformation. Dataset comparisons highlighted a small set of genes associated with Theileria -transformed leukocyte dis...

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Literature Corpus work
bbdf67bc-2ae9-52aa-941b-aff6cc1d83bb
DOI
10.1101/338160
Open publication

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