Article

Drosophila as model system to study Ras-mediated oncogenesis: the case of the tensin family of proteins

2023-07-10

Abstract excerpt

Oncogenic mutations in the small GTPase Ras contributes to ~30% of human cancers. However, tissue growth induced by oncogenic Ras is restrained by induction of cellular senescence and additional mutations are required to induce tumor progression. Therefore, it is paramount to identify cooperating cancer genes. Recently, the tensin family of focal adhesion proteins, TNS1-4, have emerged as regulators of carcinogene...

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Literature Corpus work: bee31c41-8877-579a-b9c4-dba2e5f89b38
DOI: 10.20944/preprints202307.0502.v1

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