Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Control of cell proliferation and apoptosis by mob as tumor suppressor, mats.

Cell - 11 Mar 2005

Lai Zhi-Chun, Wei Xiaomu, Shimizu Takeshi, Ramos Edward, Rohrbaugh Margaret, Nikolaidis Nikolas, Ho Li-Lun, Li Ying

Abstract excerpt

Appropriate cell number and organ size in a multicellular organism are determined by coordinated cell growth, proliferation, and apoptosis. Disruption of these processes can cause cancer. Recent studies have identified the Large tumor suppressor (Lats)/Warts (Wts) protein kinase as a key componen...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Cell Transformation, Neoplastic
Share to Conserved Sequence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microscopy, Electron, Scanning

Share to Protein Kinases

Share to Sequence Homology, Nucleic Acid

Share to Transferases (Other Substituted Phosphate Groups)

Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 15766530
DOI: 10.1016/j.cell.2004.12.036

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15766530-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Control of cell proliferation and apoptosis by mob as tumor suppressor, mats.PMID 15766530Read ↗

The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis.Semantic proximity Read ↗

The Drosophila sterile-20 kinase slik controls cell proliferation and apoptosis during imaginal disc development.Semantic proximity Read ↗

salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines.Semantic proximity Read ↗

Drosophila as model system to study Ras-mediated oncogenesis: the case of the tensin family of proteinsSemantic proximity Read ↗

LATS tumor suppressor: A new governor of cellular homeostasisSemantic proximity Read ↗

Both upstream and downstream intergenic regions are critical for the mob as tumor suppressor gene activity in Drosophila.Semantic proximity Read ↗

hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts.Semantic proximity Read ↗

Negative Regulation of YAP by LATS1 Underscores Evolutionary Conservation of the <i>Drosophila Hippo</i> PathwaySemantic proximity Read ↗

Unveiling the Tumor Suppressors: Insights from Drosophila.Semantic proximity Read ↗

Molecular characterization of human homologs of yeast MOB1Semantic proximity Read ↗

JNK pathway mediates apoptotic cell death induced by tumor suppressor LKB1 in Drosophila.Semantic proximity Read ↗

The Hippo/STE20 homolog SIK1 interacts with MOB1 to regulate cell proliferation and cell expansion in Arabidopsis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.