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The molecular and clinical role of Tensin 1/2/3 in cancer

9 Jun 2023

Abstract excerpt

Tensin 1 was originally described as a focal adhesion adaptor protein, playing a role in extracellular matrix and cytoskeletal interactions. Three other Tensin proteins were subsequently discovered, and the family was grouped as Tensin. It is now recognized that these proteins interact with multiple cell signalling cascades that are implicated in tumorigenesis. To understand the role of Tensin 1-3 in neoplasia,...

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PMID: 37296531
DOI: 10.1111/jcmm.17714

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