Article
Lentivirus-mediated long-term overexpression of specific microRNA for complementary miRNA pairs in mammalian cells
2019-07-28
Abstract excerpt
The establishment of a method that would overexpress or suppress of specific microRNA activity is essential for the functional analysis of these molecules and for the development of miRNA therapeutic applications. There already exist excellent ways to inhibit miRNA function in vitro and in vivo by overexpressing miRNA target sequences, which include miRNA ‘decoys’, ‘sponges’, or ‘antagomirs’ that are complementary...
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Identifiers and source
- Literature Corpus work
- bed7c138-7bc7-5a2a-9fd9-c45fe8fff80c
- DOI
- 10.1101/717330